Queensland COVID-19 Vaccination Safety and Efficacy Statewide Study

27 April 2022

The Queensland COVID-19 Safety and Efficacy Statewide study (QoVAX SET Statewide study) aims to improve our understanding of the short, medium and long-term impacts and effects of COVID-19 and COVID-19 vaccines in this State.

This innovative and highly translational research program is led by Professor Janet Davies and is a collaboration between health and university researchers across the Health Translation Queensland partnership.

Queensland has an unparalleled opportunity in Australia and globally, through the QoVAX SET Statewide study, to track short and long-term vaccination experiences and outcomes.

The COVID-19 vaccine rollout has been the largest coordinated vaccination program in Queensland’s history. Queensland researchers want to record and evaluate the immune response and vaccine experience of the State’s residents aged 18 years and older.

This study will look at Queenslanders’ experiences and immunity at least one to three months after their last dose of the COVID-19 vaccine. It will build our understanding of how and why our immune systems respond differently to COVID-19 vaccines. The study will consider how factors like genetic makeup, lifestyle and general health and wellbeing influence our experience.

Researchers will use this information to improve understanding of how the vaccine may need to evolve to combat new variants and who may need more health care to stay well with COVID-19. This information will assist health providers and decision-makers plan for future health events.

While the primary purpose of the QoVAX SET Statewide study is to evaluate (and manage) safety, access, and efficacy, across the community, including for priority and vulnerable peoples, a secondary purpose is to establish digitally integrated biobanking capabilities.

For this purpose, the study builds on the Networked Biobanking Project, a collaboration between Health Translation Queensland and Metro North Health and involving Queensland Pathology. This project aims to provide valuable state-wide infrastructure to underpin related secondary research.

Through the QoVAX SET Statewide study, the research team will implement a series of real-world biobank studies linking quality biospecimens, health data and informed participant consent. One of the design features of the study’s biobank and linked data repository is a research user interface that will display the types of samples and datasets available and accessible for research. This research user interface will accelerate capacity and amplify the value of the study’s systems, exemplifying the potential of sophisticated biobanks to expedite health innovations.

The QoVAX SET Statewide study is currently recruiting volunteers. Queensland adults who have received two or more doses of a COVID-19 vaccine, with the last dose received one to three months ago, are invited to participate.

For more information, please visit the QoVAX SET Statewide website.

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